Basic multiplication skills are required to master the minimum learning competencies in Mathematics; however, most pupils struggle to acquire these skills resulting to poor performance on their periodic assessments. This study was conducted with the goal of determining the effectiveness of using computer-based games in achieving Multiplication mastery of the Grade V pupils of Mabini Elementary School and Siana Elementary School. The participants were divided into two (2) groups, control and experimental, each with twenty-three (23) participants. The study employed the experimental research design using a validated pretest-posttest questionnaire. Based on findings, the experimental group improved from Did Not Meet Expectation to Outstanding, demonstrating mastery of multiplication while the control group improved from Did not Meet Expectation to Very Satisfactory. Demonstrated by the computed significance level, there is a significant difference in the participants’ performance levels before and after the intervention. Thus, the use of computer-based games is rerecommended to achieve mastery in multiplication.